levomilnacipran (Fetzima)

Meet with a licensed provider online to explore if an antidepressant medication like levomilnacipran (Fetzima) may be right for you.

Treatment for:
depression

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How prescribing works

  • 1

    Find the right provider

    Browse providers online or call us and we’ll help you find someone who accepts your insurance and fits your needs. Pick a time that works for you and choose how you’d like to pay.

  • 2

    Get started with treatment

    At your first session, share what you’re experiencing and what you’re hoping to get out of treatment. Together, you’ll discuss your options—including whether medication might be a good fit. If so, your provider can send a prescription directly to your local pharmacy.

  • 3

    Track your progress

    Your provider will check in regularly to make sure your treatment plan is working for you and adjust as needed.

What is an SNRI?

A serotonin-norepinephrine reuptake inhibitor (SNRI) is a class of medication commonly used to treat mental health conditions like anxiety, depression, OCD, and PTSD.

How does an SNRI work?

SNRIs increase the availability of serotonin and norepinephrine in the brain. Serotonin is a naturally-occurring brain chemical that supports the regulation of mood and memory; norepinephrine is also a naturally-occurring brain chemical that supports focus, attention, and energy.

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FAQs about levomilnacipran (Fetzima)

What is levomilnacipran (Fetzima) used for?

Levomilnacipran (Fetzima) is used to treat major depressive disorder (MDD) or depression. It works as a serotonin-norepinephrine reuptake inhibitor (SNRI) to increase levels of the brain chemicals serotonin and norepinephrine.

Should I take levomilnacipran (Fetzima) in the morning or night?

Levomilnacipran may be taken in the morning or at night. The time of day you take the medication depends on your response to the medication, other medications you may be taking, and what works best for you. Try to take levomilnacipran at the same time daily—it's important to stick with a regular dosing schedule when taking the medication.

Is levomilnacipran (Fetzima) a stimulant?

No, levomilnacipran is not a stimulant medication. However, the medication works by increasing levels of serotonin and norepinephrine in the brain, which can improve your mood and give you energy.

Does levomilnacipran (Fetzima) cause weight gain or loss?

No, weight gain or loss weren't commonly reported side effects of levomilnacipran. However, you may experience nausea and/or vomiting with the medication, which could cause some temporary weight loss. Taking levomilnacipran may also cause increased appetite, possibly leading to some weight gain. If you have concerns about weight gain or loss with levomilnacipran, talk with your provider.

Does levomilnacipran (Fetzima) help with anxiety?

Levomilnacipran is approved to treat depression. However, it may sometimes also be used off-label to treat anxiety since, in studies of the medication, some people with anxiety experienced improvements in their symptoms while taking it. If you're interested in learning more about using levomilnacipran for anxiety, talk with your provider.

Does levomilnacipran (Fetzima) make you sleepy?

No, sleepiness isn't a side effect of levomilnacipran. If you experience sleepiness while on the medication, talk with your provider. In some cases, your symptoms may be related to other causes, such as other medications or conditions you may have.

How long do levomilnacipran (Fetzima) side effects last?

Typically, mild side effects of levomilnacipran are temporary and go away as you keep taking the medication. However, levomilnacipran may also cause some serious side effects that can last or even be dangerous, such as some sexual side effects, seizures, high blood pressure, increased heart rate, suicidal thoughts or behavior, or bleeding. If you experience side effects that are bothersome or don't go away, talk with your provider right away to discuss your options. If you feel you're having a medical crisis, call 911 or go to your nearest emergency medical center right away.

Can I get a prescription online?

You can meet with a licensed provider at Thriveworks, in person or online depending on your state. If it’s clinically appropriate, they may prescribe medication for a diagnosed mental health condition. Your provider will send your prescription to a local pharmacy to be filled.

Can I use my health insurance for prescriptions and refills?

Thriveworks accepts most major insurance plans for psychiatry and therapy services. Your insurance may also cover the cost of any medication your provider prescribes, which can be filled at a local pharmacy. Check with your plan to confirm your medical and prescription coverage.

How do I get a prescription at Thriveworks?

Schedule a session with a licensed psychiatric provider at Thriveworks. After discussing your symptoms and treatment goals, your provider may recommend medication and/or additional services to help you get where you want to be.

Is Thriveworks LegitScript certified?

Yes. Thriveworks is LegitScript-certified, meaning we’ve been reviewed and verified by one of the most trusted compliance organizations in healthcare. This certification confirms that our services meet high standards for legality, safety, and transparency.

This information has been reviewed for accuracy and approved by our licensed psychiatric team. Published December 10, 2024
Dr. Scott Gordon

Accepting medication as part of your mental health care plan is an individual and often deeply personal decision. At Thriveworks, we’re here to help you understand your care options and support you on the path toward wellness. We prioritize treating the whole patient, whether through medication, therapy, or a combination of both — guided by clinical best practices and rigorously developed treatment strategies to help clients safely and efficiently resolve their symptoms.

Dr. Scott Gordon Chief Medical Officer

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