divalproex sodium (Depakote)

Meet with a licensed provider online to explore if a mood stabilizer like divalproex sodium (Depakote) may be right for you.

Treatment for:
bipolar disorder

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How prescribing works

  • 1

    Find the right provider

    Browse providers online or call us and we’ll help you find someone who accepts your insurance and fits your needs. Pick a time that works for you and choose how you’d like to pay.

  • 2

    Get started with treatment

    At your first session, share what you’re experiencing and what you’re hoping to get out of treatment. Together, you’ll discuss your options—including whether medication might be a good fit. If so, your provider can send a prescription directly to your local pharmacy.

  • 3

    Track your progress

    Your provider will check in regularly to make sure your treatment plan is working for you and adjust as needed.

What is a mood stabilizer?

Mood stabilizers are a class of medication that helps support mood stability for mental health conditions like bipolar disorder.

How does a mood stabilizer work?

Mood stabilizers work by regulating the activity of nerve cells in the brain, which can protect against manic or depressive episodes.

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FAQs about divalproex sodium (Depakote)

What is divalproex sodium (Depakote) used for?

Divalproex sodium is an anticonvulsant type of medication used to treat types of seizures, manic phases of bipolar disorder, and migraine headaches.

Does divalproex sodium (Depakote) cause weight gain or loss?

Yes, weight changes are possible due to taking divalproex sodium. Weight gain and loss are common side effects of the medication, as well as changes in appetite (increase or decrease), which could cause shifts in weight. If you're concerned about weight changes while taking divalproex sodium, talk with your provider. They can discuss ways to help you manage a healthy weight during treatment.

Is divalproex sodium (Depakote) a controlled substance?

No, divalproex sodium is not a controlled substance and isn't known to cause addiction. If you have questions about the side effects of divalproex sodium, contact your pharmacist or provider about your concerns.

Does divalproex sodium (Depakote) make you sleepy?

Yes, sleepiness is a common side effect of taking divalproex sodium. You may experience sleepiness when you begin treatment, which may gradually ease. However, until you know how the medication affects you, do not drive or perform tasks that require alertness. Talk with your pharmacist or provider if this side effect is bothersome and doesn't go away.

How long does divalproex sodium (Depakote) stay in your system?

Divalproex sodium has a half-life of 9 to 16 hours. This means it takes this long for around half the drug to leave your system. It typically takes around 5 half-lives for a drug to completely leave your system, so it will likely leave your body fully after 3 or 4 days. However, depending on other health conditions you may have, your age, and other factors, it may take longer in some cases. If you have other questions about how long divalproex sodium can stay in your system, talk with your provider.

How long does it take for divalproex sodium (Depakote) to work?

Divalproex sodium starts to work after you take a dose, and reaches maximum concentration after about 4 hours in the body. However, how long it takes to work for you depends on how you respond to the medication, the severity of your condition, and other individual factors. It may take several weeks of taking the medication before you notice an improvement in your symptoms. Talk with your provider if you have questions about divalproex sodium's effectiveness for you.

What are the side effects of divalproex sodium (Depakote)?

Some common side effects of divalproex sodium include nausea, vomiting, headache, dizziness, sleepiness, weight changes, hair loss, abdominal pain, depression, constipation, double or blurry vision, problems with coordination, insomnia, sore throat, rash, diarrhea, tremor, and infection, though these are not all the possible side effects. To learn more about all the possible side effects of the medication, talk with your pharmacist or provider.

Can I get a prescription online?

You can meet with a licensed provider at Thriveworks, in person or online depending on your state. If it’s clinically appropriate, they may prescribe medication for a diagnosed mental health condition. Your provider will send your prescription to a local pharmacy to be filled.

Can I use my health insurance for prescriptions and refills?

Thriveworks accepts most major insurance plans for psychiatry and therapy services. Your insurance may also cover the cost of any medication your provider prescribes, which can be filled at a local pharmacy. Check with your plan to confirm your medical and prescription coverage.

How do I get a prescription at Thriveworks?

Schedule a session with a licensed psychiatric provider at Thriveworks. After discussing your symptoms and treatment goals, your provider may recommend medication and/or additional services to help you get where you want to be.

Is Thriveworks LegitScript certified?

Yes. Thriveworks is LegitScript-certified, meaning we’ve been reviewed and verified by one of the most trusted compliance organizations in healthcare. This certification confirms that our services meet high standards for legality, safety, and transparency.

This information has been reviewed for accuracy and approved by our licensed psychiatric team. Published October 3, 2024
Dr. Scott Gordon

Accepting medication as part of your mental health care plan is an individual and often deeply personal decision. At Thriveworks, we’re here to help you understand your care options and support you on the path toward wellness. We prioritize treating the whole patient, whether through medication, therapy, or a combination of both — guided by clinical best practices and rigorously developed treatment strategies to help clients safely and efficiently resolve their symptoms.

Dr. Scott Gordon Chief Medical Officer

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